The Jmol image is based on pdb file 3EE9

The space filled version of NS1.
To view NS1 backbone. Note the dimer arrangment. In this form,NS1 is relatively harmless
The two yellow residues, PHE103 and MET106, form a weak connections between different structures with which NS1 associates. (rotated 180 degrees)
One of the monomers, highlighting the hydrophobic pocket which attaches to CPSF30-Binding site. This is another way the NS1 disables the immune system.
The active site(Thr94 or Ile95 or Glu96 or Glu97)highlighted in red here, attaches to the Trim25 protein. In the words of Dr. Shannon Colton... If NS1 binds to Trim25, Trim25 can no longer add ubiquitinto the target protein, RIG1. This then means that the signal cascade to activate interferon production (antiviral proteins that the host canproduce when it detects viral invasion to help signal for the destruction of the invading virus), is inhibited and this means interferons are not made. Adv to the virus.