Morphine
(Converted Wikipedia SMILES) https://en.wikipedia.org/wiki/Morphine
 Morphine has two regions (show in gold) that interact with(bond) the mu opiod receptor
A wire framed model illustrating the two regions(shown in gold) that interact wtih the mu opiod receptor.
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Some Important References
1. Opiod Structure Activity Relationship. (2019). Slideshare.net. Retrieved 17 March 2019, from https://www.slideshare.net/sujisusanth/opiod-sar-48199676
2. Opioids Opium poppy cultivation - ppt download. (2019). Slideplayer.com. Retrieved 17 March 2019, from https://slideplayer.com/slide/3318272/
3. Increased Therapeutic Action Project. (2019). Natsci.parkland.edu. Retrieved 17 March 2019, from http://natsci.parkland.edu/che/106/sonnichsen/Projects/Increased%20Therapeutic%20Action%20Project.htm 4. Pasternak, G., & Pan, Y. (2013). Mu Opioids and Their Receptors: Evolution of a Concept. Pharmacological Reviews, 65(4), 1257-1317. doi:10.1124/pr.112.007138

Heroin
(Converted Wikipedia SMILES) en.wikipedia.org/wiki/Heroin
 Heroin's two binding regions (gold) to the mu opioid receptor.
Heroin's two binding regions(gold) shown in wireframe style.
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It should be noted that heroin quickly metabolizes to morphine in the body.


Codeine (based on Converted Wikipedia SMILES File)
Spacefilled model showing the mu opioid binding sites(gold) of codeine.
Codeine does not bind as well to the mu opioid receptor as morphine does because of this methyl group.
Wire-framed model showing the mu opiod binding sites(gold) of codeine.
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