Glycoprotein Complex Pre Fusion State
(based on 5JQ3.pdb)
The model shown at startup shows the prefusion state of the Ebola Glycoprotein colored in cpk.
This model shows the prefusion state of the Ebola Glycoprotein in spacefill with GP1 olivedrab and GP2 colored in palegoldenrod.
The two subunits are shown in backbone, GP1 in olivedrab, and GP2 in palegoldenrod.
Focusing just on GP2
Some key sites include the internal fusion loop shown in gold, the repeating heptad region also critical for fusion in blue, important sites in keeping the GP1 and GP2 peptide units together and in the same arrangement in cyan.

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The Glycoprotein Trimer Cap
(based on 3CSY.pdb)
The model shown at startup shows the spacefilled prefusion glycoprotein trimer cap colored in cpk.
The prefusion structure of the GP complex (GP1 and GP2), highlighting the GP1 and GP2 subunits.
The structure of the GP complex highlighting the GP1 and GP2 subunits in backbone using the chain colors.
The GP1 and GP2 subunits in backbone illustrating the trimer nature of the cap
The GP1 subunits in backbone. Residues in these attach to the cell receptors.
The GP2 subunits in backbone. Residues in these allow for the fusion of the viral and cell membranes.

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G2 Post Fusion Conformation
(based on 2ebo.pdb)
The model shown at startup shows the spacefilled GP2 trimer in the fusion-active conformation colored in cpk.
A single Glycoprotein 2 (GP2) in fusion-active conformation in cpk colors
A single Glycoprotein 2 (GP2) in backbone colored in light blue
GP2 in Trimer active Conformation
GP2 illustrating the polar(in red) and nonpolar(in blue) of the active trimer conformation
GP2 modeled in spacefill form illustrating the hydrophobic nature (in blue) of the core membrane fusion area of GP2 (other parts of molecule are colored by chain part of the trimer)

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