SMART Team Investigations


Escherichia coli Toxin:  Watch What You Eat!
(2006-2007 SMART Team)

                    Background Summary

Jmol animations The Binding Sites and Action of the E-coli toxin 
E-Coli:  Friend or Foe... 
  SMART Team Members


Here is a picture of Subunit A (left), or the active site, of the shiga toxin.  On the right, there is E. coli after the glycosidase cleavage.


This here is the image of the B subunit, or the binding domain, of the E. coli threat.

E. coli uses the following pdb file: 1R4P.pdb

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Background images are from pdb files downloaded from the Protein Data Bank.

The images are of catalase, single stranded DNA, and of insulin. 
The pdb file numbers (Brookhaven Extension numbers) are 4BLC, 1EW1,  and 2CEU.