SMART Team Investigations

 

Escherichia coli Toxin:  Watch What You Eat!
(2006-2007 SMART Team)

 Summary
                    Background Summary

                   
Jmol animations The Binding Sites and Action of the E-coli toxin 
  PowerPoint 
                       
E-Coli:  Friend or Foe... 
  SMART Team Members


     

Here is a picture of Subunit A (left), or the active site, of the shiga toxin.  On the right, there is E. coli after the glycosidase cleavage.

 




This here is the image of the B subunit, or the binding domain, of the E. coli threat.

 
E. coli uses the following pdb file: 1R4P.pdb

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Background images are from pdb files downloaded from the Protein Data Bank.
http://www.rcsb.org/pdb/home/home.do

The images are of catalase, single stranded DNA, and of insulin. 
The pdb file numbers (Brookhaven Extension numbers) are 4BLC, 1EW1,  and 2CEU.