"Misfiring"... Shutting down Mutant EGFR
(2008-09 SMART Team)

•Summary
                      • Jmol Animations EGFR and RAS
                            •EGFR & Lapatibin: a Chemotherapy
                            •RAS and GTP: A Site for Possible Signal Interference
                            •Guanosine Phosphates... Important Signaling Agents
                      • EGFR Abstract
                                    •Ras Abstract
•3 PowerPoints Describing the Story
                         •Controlling a Killer Malfunction
                              • Cancer: Modeling Different Methods to Control It
                              •Controlling Cancer
•SMART Team Members

Epidermal Growth Factor Receptor (EGFR)

RAS GTPase

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Background images are from pdb files downloaded from the Protein Data Bank.
http://www.rcsb.org/pdb/home/home.do

The images are of catalase, single stranded DNA, and of insulin.
The pdb file numbers (Brookhaven Extension numbers) are 4BLC, 1EW1, and 2CEU.