SMART Team Investigations


"Misfiring"... Shutting down Mutant EGFR
(2008-09  SMART Team)

Jmol Animations EGFR and RAS
                            EGFR & Lapatibin: a Chemotherapy
                            RAS and GTP:  A Site for Possible Signal Interference
                            Guanosine Phosphates... Important Signaling Agents
EGFR Abstract
                                    Ras Abstract
3 PowerPoints Describing the Story
                         Controlling a Killer Malfunction
                              Cancer:  Modeling Different Methods to Control It

                              Controlling Cancer
SMART Team Members


Epidermal Growth Factor Receptor (EGFR)




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Background images are from pdb files downloaded from the Protein Data Bank.

The images are of catalase, single stranded DNA, and of insulin. 
The pdb file numbers (Brookhaven Extension numbers) are 4BLC, 1EW1,  and 2CEU.