SMART Team Investigations

Influenza Hemagglutinin & The Threat of Avian Flu
(2005-2006 SMART Team)

•Summary
              
•Influenza Hemagglutinin Summary
              
•Jmol Animations The high and low pH forms of Influenza Hemagglutinin
•
A
Powerpoint  Analyzing the Avian Flu  
•
SMART Team Members


The strand here is the file 5HMG.pdb which shows HA in a pH solution that was approximately neutral.
 


This strand is 1HTM.pdb where the HA enters into a new pH environment of about 5, thus changing the physical appearance and conformation of the molecule.
 

David Goodsell's and the Protein Data Bank's Molecule of the Month  

 

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Background images are from pdb files downloaded from the Protein Data Bank.
http://www.rcsb.org/pdb/home/home.do

The images are of catalase, single stranded DNA, and of insulin. 
The pdb file numbers (Brookhaven Extension numbers) are 4BLC, 1EW1,  and 2CEU.